Chris RuiWen Kuo, Brian Lipworth
European Respiratory Journal 2019; DOI: 10.1183/13993003.02102-2018
Allergic asthma is characterised by the presence of circulating specific immunoglobulin E (IgE) or positive skin prick test (SPT) to common aeroallergen. Type-2 inflammatory (T2) cytokines stimulates IgE synthesis in response to aeroallergen, resulting in chronic eosinophilic (Eos) airway mucosal inflammation.
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Conflict of interest: Dr. Kuo reports personal fees from Pfizer/Bristol-Myers Squibb, personal fees from Circassia, outside the submitted work.
Conflict of interest: Dr. Lipworth reports grants and personal fees from AZ, personal fees and other from Teva, personal fees from Novartis, personal fees from Sanofi, non-financial support from GSK, grants and personal fees from Chiesi, personal fees from Thorasys, during the conduct of the study; grants and personal fees from Meda, grants from Janssen, grants from Roche, personal fees from Lupin, grants and personal fees from Boerhinger Ingelheim, personal fees from Cipla, personal fees from Sandoz, personal fees from Dr Reddys, outside the submitted work. The son of BJL is an employee of AstraZeneca.