Objective: Solitary fibrous tumors (SFTs) are rare primary neoplasms that most commonly involve the pleura, mediastinum and lung arising from the submesothelial tissue. They usually show a benign clinical course. Immunohistochemical analysis is used to make the diagnosis. We reviewed our experience to obtain a better understanding of this disease.
Methods: In this study, we reviewed 13 patients, 11 male, 2 female, who were admitted to our hospital in the period 2006-2014. Their age ranged from 25-44 years. All but one were asymptomatic. In 12 cases it was an incidental finding on a chest CT scan performed for another reason. In the last case the patient came hemodynamically unstable due to rupture of the tumor in the pleural cavity causing a massive hemothorax.
Results: All but one were electively led to the operating room and complete resection was performed either through thoracotomy or video-assisted thoracic surgery (VATS). The patient suffering from massive hemothorax was submitted urgently to thoracotomy and the hemorrhage stopped as soon as the tumor was excised. In this case the tumor expanded to the spine and a second operation by the neurosurgeons offered to the patient definitive cure. The postoperative course was uneventful and there was no recurrence during 12-93 (mean 42) months of follow-up in all our cases.
Conclusions: 1. SFTPs are rare tumors usually benign and asymptomatic. 2. Complete resection of SFTs is curative. 3. Morphological and pathological features are important in distinguishing them from other tumors and in predicting clinical behaviour.