Berita Kesehatan
The Clinical and Epidemiological Features of Pneumonia in Young Men in Organized Collectives
Selasa, 13 Nov 2018 14:06:12


Streptococcus pneumoniae (S. pneumoniae) occupies a leading place in the etiology of community-acquired pneumonia (CAP) in the adults.

The aim: to study of the clinical and epidemiological features of CAP in men in organized collectives.

The methods: The study included 265 men 18-26 years old with CAP (114 vaccinated and 151 non-vaccinated Pneumo 23 (Sanofi Pasteur, France). The survey included questionnaires, clinical study,blood analysis, microbiological examination (ME) of sputum, definition of Antigen capsules of S. pneumoniae in urine using test Binax NOW S. pneumoniae (Alere Inc., United States), a study of CRP by quantitative method and the microflora of the throat using polymerase chain reaction, chest x-rays and pulsoximetry.

The results: Found that CAP risk factors in men were low anthropometric indicators, diseases of the upper respiratory tract, 1 and more cases of CAP, lack of vaccination against S. pneumoniae,tobacco smoking. The risk of CAP in the first 100 days of service among non-vaccinated was 6.96 (95% CI 3.39-14.58; p < 0.001), compared to vaccinated and clinical manifestations of CAP were more severe. S. pneumoniae in secret from the throat was in 48.8% of patients. In ME of the sputum from vaccinated and non-vaccinated most commonly allocated H. influenzae (24.1 and 20.0%; p > 0.05), Streptococcus spp. (19.0 and 36.0%; p = 0.48), S. pneumoniae (10.3 and 4.1%; p > 0.05). Test Binax NOW S. pneumoniae (+) detected at 2.9% vaccinated and 1,4% non-vaccinated patients with CAP.

The conclusions: Vaccination with Pneumo 23 reduces the incidence of pneumococcal CAP in patients at risk, severity of the CAP and the period of the recovery.