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Pulmonary function interpretative strategies: from statistics to clinical practice
Selasa, 19 Jul 2022 12:06:29

Vito Brusasco, Riccardo Pellegrino

European Respiratory Journal 2022 60: 2200317; DOI: 10.1183/13993003.00317-2022


In 2005, the European Respiratory Journal published a series of American Thoracic Society (ATS)/European Respiratory Society (ERS) consensus documents on the standardisation of pulmonary function testing (PFT), which ended with an article on interpretative strategies [1]. Despite being well received by the scientific community (with over 3500 citations so far), that article generated controversy in a couple of areas and left some questions open due to insufficient evidence available at that time. After more than 10 years, the two societies felt the need to update the whole series, with the main purpose of addressing recent technical advancements. The final document published in the current issue of the European Respiratory Journal [2] is again on interpretative strategies. The difference between the two interpretative documents is that the current one is focused on technical sources of uncertainty, rather than on algorithms for lung function planning and interpretation in the clinical context.

The application of suitable reference equations based on a robust statistical approach is central to pulmonary function testing, but the complexity of lung physiology makes the interpretation of results in individual patients challenging


  • Conflict of interest: The authors declare no conflict of interest.

  • Received February 10, 2022.
  • Accepted February 13, 2022.