The underlying pathophysiological determinants of asthma and chronic obstructive pulmonary disease (COPD) are related in complex ways. Importantly however, post-bronchodilator FEV1-reversibility may occur in approximately 50% of COPD patients  whilst epidemiological  and magnetic-resonance-imaging (MRI) studies  suggest that in asthmatics, FEV1-reversibility may diminish over time. As compared to patients with asthma or COPD alone, patients with co-existing asthma and COPD report worse clinical outcomes  and increased healthcare costs  and burden [4, 5].
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Conflict of interest: Dr. Serajeddini has nothing to disclose.
Conflict of interest: Ms. Eddy has nothing to disclose.
Conflict of interest: Dr. Licskai has nothing to disclose.
Conflict of interest: Dr. McCormack has nothing to disclose.
Conflict of interest: Dr. Parraga has nothing to disclose.